Exfoliating Neisseria gonorrhoeae

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Neisseria gonorrhoeae

Two fi-lactamase-producing strains of Neisseria gonorrhoeae were studied. The substrate profile, molecular weight, and isoelectric point of their ,8-lactamases were similar to those of the TEM-1 enzyme produced by many gram-negative bacilli. The gonococcal f8-lactamase was cell bound during exponential growth and was most likely located in the periplasm. Penicillin hydrolysis was efficient in i...

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Neisseria gonorrhoeae

Expression of Type IV pili by the bacteria! pathogen Neisseria gonorrhoeae appears to be essential for colonization of the human host. Several N. gonorrhoeae gene products have been recently identified which bear homology to proteins invoived in pilus assembly and protein export in other bacterial systems. We report here the isolation and characterization of transposon insertion mutants in N. g...

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ژورنال

عنوان ژورنال: Nature Reviews Microbiology

سال: 2020

ISSN: 1740-1526,1740-1534

DOI: 10.1038/s41579-020-0375-2